منابع مشابه
PNA-mediated Whiplash PCR
In Whiplash PCR WPCR autonomous molecular compu tation is achieved by the recursive self directed polymerase extension of a mixture of DNA hairpins A barrier confronting e cient implementa tion however is a systematic tendency for encoded molecules towards backhybridization a simple form of self inhibition In order to examine this e ect the length distribution of extended strands over the cours...
متن کاملMetal binding to bipyridine-modified PNA.
Substitution of natural nucleobases in PNA oligomers with ligands is a strategy for directing metal ion incorporation to specific locations within a PNA duplex. In this study, we have synthesized PNA oligomers that contain up to three adjacent bipyridine ligands and examined the interaction with Ni2+ and Cu2+ of these oligomers and of duplexes formed from them. Variable-temperature UV spectrosc...
متن کاملEGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method
Introduction. Rebiopsies have become more crucial in non-small cell lung cancer (NSCLC). Instead of invasive biopsies, development of collecting biological data of the tumor from blood samples is expected. We conducted a prospective study to assess the feasibility of detection of epidermal growth factor receptor (EGFR) mutation in plasma samples. Method. NSCLC patients harboring EGFR activating...
متن کاملSelective recognition of DNA from olive leaves and olive oil by PNA and modified-PNA microarrays
PNA probes for the specific detection of DNA from olive oil samples by microarray technology were developed. The presence of as low as 5% refined hazelnut (Corylus avellana) oil in extra-virgin olive oil (Olea europaea L.) could be detected by using a PNA microarray. A set of two single nucleotide polymorphisms (SNPs) from the Actin gene of Olive was chosen as a model for evaluating the ability...
متن کاملDetection of genetically modified organisms by electrochemiluminescence PCR method.
With the development of biotechnology, more and more genetically modified organisms (GMOs) have entered commercial market. Because of the safety concerns, detection and characterization of GMOs have attracted much attention recently. In this study, electrochemiluminescence polymerase chain reaction (ECL-PCR) combined with hybridization technique was applied to detect the GMOs in genetically mod...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2012
ISSN: 1538-4047,1555-8576
DOI: 10.4161/cbt.19075